2015-12-23

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Some medicines known to cause dry mouth include: Antianxiety drugs and antidepressants. Anticholinergics, drugs used to treat many conditions, such as urinary incontinence, overactive bladder and chronic obstructive pulmonary disorder. Antihistamines, decongestants and some pain medicines.

Polypharmacy, or the use of multiple medications, and the interaction between these medications has been shown to increase the incidence of xerostomia and SGH in the elderly because of the cumulative effects of combining drug therapies in an individual with multiple systemic problems (Thomson et … User Reviews for Pilocarpine to treat Xerostomia. Also known as: Salagen Pilocarpine has an average rating of 6.2 out of 10 from a total of 9 ratings for the treatment of Xerostomia. Xerostomia is reported more commonly in women (10, 18-20), smokers (12, 20), and individuals with symptoms of depression (9, 20). Xerostomia is also associated with impaired general health (12, 21) and use of medication – in particular, a high number of medications or xerogenic medications .

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Xerostomia (dry mouth) may be a side-effect of medication. It is also caused by irradiation of the head and neck region or by damage to or disease of the salivary glands. Patients with a persistently dry mouth may develop a burning or scalded sensation and have poor oral hygiene. One of the most prevalent causes of xerostomia is medication. Anticholinergics, such as psychotropic agents and antihistamines, and diuretics can dry the oral mucosa. Results: The prevalence rate of xerostomia in the medicated hypertensive group was 50% whereas only 25.5% of the control group had xerostomia (p < 0.05). Using modified Schirmer test (MST), the mean unstimulated salivary flow rate of the medicated hypertensive group (23.11 +/- 6.08 mm/3 min) was significantly lower than that of the control group (31.30 +/- 3.36 mm/3 min) (p < 0.05).

Some medicines known to cause dry mouth include: Antianxiety drugs and antidepressants. Anticholinergics, drugs used to treat many conditions, such as urinary incontinence, overactive bladder and chronic obstructive pulmonary disorder. Antihistamines, decongestants and some pain medicines.

[ncbi.nlm.nih.gov] […] correlates more closely with symptoms of xerostomia than stimulated flow Diverse etiology includes idiopathic, autoimmune disease, drugs (anticholinergics), radiation therapy Causes 2019-10-21 Xerostomia that occurs with abrupt onset after head and neck trauma may be caused by nerve damage. Concomitant presence of dry eyes, dry skin, rash, or joint pain, particularly in a female patient, suggests a diagnosis of Sjögren syndrome. Xerostomia (also termed dry mouth as a symptom or dry mouth syndrome as a syndrome ) is dryness in the mouth ( xero- + stom- + -ia ), which may be associated with a change in the composition of saliva , or reduced salivary flow ( hyposalivation ), or have no identifiable cause . This symptom is very common and is often seen as a side effect of many types of medication.

Up to 30% of Americans experience xerostomia, 2-8 with elders affected more. 9 Many things cause a sticky, dry mouth— scary movies, dental cotton before a procedure, heredity, snoring, or mouthbreathing during a cold—but medication is the most frequent cause. 10-12 Most medications associated with dry mouth affect the sympathetic nervous system, thickening and limiting the flow of saliva. 13

The only protective factor against xerostomia identified was medications that induce hypersialorrhea OR=0.81, 95% CI (0.67-0.98), p=0.03. 2019-07-02 2015-12-23 Xerostomia is the subjective feeling of oral dryness.

Xerostomia medication

Results: The prevalence rate of xerostomia in the medicated hypertensive group was 50% whereas only 25.5% of the control group had xerostomia (p < 0.05). Using modified Schirmer test (MST), the mean unstimulated salivary flow rate of the medicated hypertensive group (23.11 +/- 6.08 mm/3 min) was significantly lower than that of the control group (31.30 +/- 3.36 mm/3 min) (p < 0.05). Se hela listan på mayoclinic.org Se hela listan på mayoclinic.org Up to 30% of Americans experience xerostomia, 2-8 with elders affected more. 9 Many things cause a sticky, dry mouth— scary movies, dental cotton before a procedure, heredity, snoring, or mouthbreathing during a cold—but medication is the most frequent cause. 10-12 Most medications associated with dry mouth affect the sympathetic nervous system, thickening and limiting the flow of saliva. 13 Dry mouth, also known as Xerostomia, occurs when salivary glands don't make sufficient saliva to prevent the drying of the mouth. Dry mouth can be a symptom or side-effect of other conditions and survey, xerostomia was the most common.
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Dry Mouth. Sandra Wilkie RDH, BS. Idaho State University. MSDH Program Risk Factors for Xerostomia Medication Induced Xerostomia. The main causes are medical treatment, polymedication and diseases. Xerostomia generates an increase of pathogenic bacteria in a pathogenic biofilm, which  Interest of the Sialendoscopy Associated With a Local Injection of Corticosteroids in the Treatment of Radio-induced Xerostomia in Comparison With the  Avslutad.

Avoid/discontinue any medications that may cause or exacerbate xerostomia in collaboration with physician/nurse practitioner and pharmacist Amifostine – a cytoprotectant agent that reduces the incidence/severity of acute/chronic xerostomia in patients receiving radiation therapy for head and neck cancer. Use may be considered controversial.
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Xerostomia medication




induced xerostomia in head and neck cancer patients. J Clin Oncol. 1993;11:1124-1131. 2. Vivino FB, et al. Pilocarpine tablets for the treatment of dry mouth and 

Some medications cause dry mouth because they have anticholinergic side effects — that is, they block the action of  Medications can cause dry mouth in different ways. For example, they can suppress the production of acetylcholine (ACh), a neurotransmitter that stimulates the  7 Jun 2020 There are numerous causes of xerostomia; the most common cause is medication side effects, followed by Sjogren syndrome (SS) and  8 May 2020 There is a long list of pharmacological sialogogues, but only two drugs are approved by the FDA for the treatment of xerostomia: pilocarpine and  22 May 2018 These Are the Most Common Drugs that Cause Xerostomia there are over 1,800 prescribed medications that have dry mouth listed as one of  Xerostomia refers to a subjective sensation of a dry mouth , its frequently, but not always associated with salivary gland hypofunctions.


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Results: The prevalence rate of xerostomia in the medicated hypertensive group was 50% whereas only 25.5% of the control group had xerostomia (p < 0.05). Using modified Schirmer test (MST), the mean unstimulated salivary flow rate of the medicated hypertensive group (23.11 +/- 6.08 mm/3 min) was significantly lower than that of the control group (31.30 +/- 3.36 mm/3 min) (p < 0.05).

Gerodontology 2003; 20: 64–77.

Xerostomia is the subjective sensation of oral dryness, which can be influenced by etiological factors including the use of several types of medications, Sjogren’s and metabolic syndromes, head

Older adults are  Treatment.

Examples are drugs with anticholinergic properties such as Atropine, but also alpha and beta blockers. Other causes are chronic parotitis, Sjögren’s syndrome, salivary duct obstruction, diabetes, and HIV and radiation therapy to the salivary glands. Xerostomia is the subjective sensation of oral dryness, which can be influenced by etiological factors including the use of several types of medications, Sjogren’s and metabolic syndromes, head Medication is the number one cause 1,3,4 of Dry Mouth as it is a side effect of many common medicines 5 including antihistamines, antidepressants, diuretics, and sedatives.